Steven Holtzman joined Decibel Therapeutics as president chief and executive officer in 2016. Decibel discovers and develops novel therapeutic approaches to treat hearing loss and other hearing disorders. Prior to Decibel, he served as executive vice president, corporate development at Biogen, Inc. At Biogen, Steve created and led the program leadership and management group through eight new drug approvals. He also led the business development and M&A group through successful completion of numerous transactions. Prior to Biogen, Steve served as the founder, chief executive officer and chair of the board of directors of Infinity Pharmaceuticals, Inc., a cancer drug discovery and development company.  He was also an early leader and the chief business officer of Millennium Pharmaceuticals (now Takeda Oncology), a pioneer in largescale genetics and genomics, and was a founder, member of the board and the executive vice president of DNX Corporation, the first transgenic animal company. Steve is a member of the boards of directors of Visterra, Warp Drive Bio, and Molecular Partners. He serves as a strategic business advisor to Humatics, Compugen, and Marauder Therapeutics.  In the not-for-profit arena, Steve is currently a trustee of the Berklee College of Music and previously served as the vice chairman of the board of trustees of the Hastings Center for Ethics and the Life Sciences. From 1996 to 2001, he served as a Presidential appointee to the U.S. National Bioethics Advisory Commission. Steve received his B.A. in philosophy from Michigan State University and his B.Phil. graduate degree in philosophy from Corpus Christi College, Oxford University, which he attended as a Rhodes Scholar.
Michael Su joined Decibel as chief scientific officer in August 2016. Prior to Decibel, Michael served as co-founder and senior vice president of research and development at Agios Pharmaceuticals. Michael has more than 25 years of organization, project management and scientific experience in the biotechnology industry. During his time at Agios, he led the team responsible for identifying oncogenic causes for the company’s lead mutant isocitrate dehydrogenase programs and led the discovery of the resulting drug candidates, which are currently in late-stage clinical development. In addition, he chaired the Agios-Celgene joint research collaboration from 2010 to 2013 and led drug discovery in the rare genetic diseases franchise. From 2004 to 2006, he served as general director and vice president of the Biomedical Engineering Research Laboratory (BEL) at ITRI in Taiwan. Prior to that, he spent 14 years in a number of roles, concluding his tenure as program executive and vice president of the Novartis kinase collaboration for Vertex Pharmaceuticals. Michael completed his Ph.D. in biochemistry from Duke University followed by accepting the Helen Hay Whitney fellowship in biochemistry and molecular biology at Harvard University. He has been published over 50 times with more than 20 issued and pending patents.

John Keilty joins Decibel from Third Rock Ventures where he served as the general manager of platform operations, responsible for the development and implementation of technology roadmaps for companies across the portfolio. Prior to this role, John was the vice president of information technology and informatics at Infinity Pharmaceuticals where he owned information systems, software development, computational science, biostatistics, clinical data management and clinical informatics. Before joining Infinity in 2002, John was an early member of Millennium Pharmaceuticals where he held various roles of increasing responsibility, with broad ownership for the creation, management, implementation and transfer of many of the company’s core genomic technologies. Before Millennium, John worked in the Howard Hughes lab of Michael Green at the University of Massachusetts Medical Center, focusing on basic research in transcription and gene splicing.

John received his B.A. in biology from Clark University and his M.S. in bioinformatics from Brandeis University.

Paula Cobb joined Decibel in September 2016 as executive vice president of corporate development. Prior to Decibel, Paula served as senior vice president of the rare disease group at Biogen. With more than 13 years of experience in the biotechnology industry, Paula has led teams to three new drug approvals and played key roles on four product launches. At Biogen, Paula served in various senior and global roles. As senior vice president of the rare disease group, she was responsible for the company’s marketed hemophilia assets and Phase 3 programs in spinal muscular atrophy and neuropathic pain. Prior to this role, Paula managed the multiple sclerosis franchise, led new product commercialization for early pipeline programs, served as chief of staff to the CEO, and held various operational management roles with Biogen in Europe. Before Biogen, Paula worked for various consulting groups in the Boston area. Paula graduated cum laude from Amherst College with a Bachelor of Arts degree in political science and English. She also received an MBA from Harvard University Graduate School of Business Administration.
John Lee joined Decibel in September 2016 as senior vice president of pharmaceutical development, and brings over 20 years of R&D, operational and leadership experience in the biotechnology industry. Prior to Decibel, he served as senior vice president of pharmaceutical development at Infinity Pharmaceuticals. Over the course of his 15 years at Infinity, John held roles of increasing responsibility and leadership. Most recently, he was responsible for chemistry, manufacturing and control (CMC), analytical sciences, formulation sciences, and clinical supply and distribution for the company’s drug candidates across all phases of global clinical development, as well as co-chair of Infinity’s operational leadership team. Prior to Infinity, John was a new product manager at Corning Life Science where he was responsible for developing new life science products from Corning research and technologies. Before Corning, John was an early member of Millennium Pharmaceuticals and played a key role in the successful positional cloning of the mouse obesity gene tubby, before taking on the role of project lead for an ovarian cancer diagnostic program. Prior to Millennium, John worked in the developmental chronobiology lab of Steven Reppert at Massachusetts General Hospital, where he focused on cloning G-protein coupled receptors and circadian biology. John received his bachelor of science in materials science and engineering from the Massachusetts Institute of Technology.
Anna Trask joined Decibel as VP, People, Community and Culture in January 2018, bringing with her nearly 30 years of experience in the field of Human Resources. Prior to Decibel, Anna served as Senior Director, Human Resources, at the Dana Farber Cancer Institute; Chief Human Resource Officer at Boston Medical Center Healthnet and leadership positions at Neighborhood Health Plan, Pine Manor College and Harvard Pilgrim/Harvard Community Health Plan.  Across these roles she was responsible for creating and implementing innovative organizational design and development programs to improve critical areas such as: transparency, efficiency and effectiveness; professional development; and organizational diversity. Anna graduated with a Bachelor of Arts degree in Politics from Mount Holyoke College, and a Masters in Psychology from Boston University.

Ronald Vigliotta joined Decibel as senior director, finance in November 2016 and has more than 20 years of diverse accounting and finance experience, including in both public and private biotechnology companies.  Prior to Decibel, Ron served as senior director, finance at Warp Drive Bio for three years, where he led both the accounting and finance functions.  Prior to Warp Drive Bio, Ron worked at Infinity Pharmaceuticals for seven years where he held various roles of increasing responsibility including Controller. Before Infinity, he spent five years at Hilb, Rogal and Hobbs, an insurance brokerage company, serving as agency controller. He also worked at Ernst & Young  for six years in the assurance and advisory business group servicing clients in multiple industries. Ron graduated from Fairfield University with a bachelor of science in accounting and finance and is a certified public accountant.